Tramadol stays in your system for several days. It remains for 48 hours in the blood and anywhere from 24 to 72 hours in the urine. Your saliva will show up for as long as 48 hours, while in your hair, it remains for upwards of 90 days.

TestSalivaBloodUrineHair
Time48 hour48 hours24-72 hours90 days

This Tramadol proves to be a synthesized opioid analgesic medicine that is utilized effectively to address moderate to more severe pain. Pharmaceutical brands sell it under such names as FusePaq, ConZip, Rybix, Synapryn, Ultram, and Ryzolt. This medication is restricted for children, so it should not be given to them without expressed orders from a capable physician.?

Tramadol is similarly classed as a Schedule IV controlled substance in the U.S. as with Valium and Xanax. Since this is not your standard addicting drug, Tramadol is rarely screened for on either ten-panel of 5-panel drug tests. It does appear on some drug tests that check for addiction to prescription pain medicines.

How Long Until You Feel The Impacts of Taking Tramadol?

Tramadol impacts your opioid pain receptors of the brain as well as your central nervous system. It will also hinder the reuptake of several neurotransmitters, including norepinephrine and serotonin. 

The effects reach their peak effectiveness from two to four hours after consumption. Extended relief pills last for longer durations. 

When the medicine is active, Tramadol depresses your breathing and constricts the pupils. Tramadol also decreases the motility of your body’s digestive system, meaning, food will require more time to digest, causing potential constipation. You might also suffer from the following symptoms:

  • Itching
  • Sweating
  • Flushing
  • Reddened Eyes
  • Faintness or Dizziness After Standing from a Reclining Position

How Long Will Tramadol Effects Last?

The Food and Drug Administration (FDA) warns that Tramadol’s half-life within the blood is approximately five to nine hours. For those who have taken several doses, this will prolong the effects. It requires as much as from five to six times for total elimination to occur as it does for the half-life to expire.

How long does Tramadol stay in your system?

Your liver is where Tramadol breaks down. It is the kidneys that will flush the remains of the medication out in the form of your urine. As much as 30 percent of the medication becomes flushed out with no change in form. The remainder becomes converted to several metabolites that get excrete after the fact. 

Differences Between Drops, Injections, and Pills

Tramadol exists in a drop, injection, and pill form. With the pill form of the medication, the body will absorb it slower and excrete it far slower than with the other injection or drop versions. 

Dangers of False Positive Tests

No known substances will cause a false positive to occur for Tramadol. Yet the medication’s metabolites can trigger false positives for other controlled substances like buprenorphine and PCP. This means that you should always talk with your testing facility before you have your drug test to ensure that you are taking a prescription for Tramadol ahead of time. 

Detection Time for Tramadol

Not everyone can metabolize Tramadol effectively. Roughly seven percent of individuals possess a reduced activity in the cytochrome P-450 isoenzyme CYP2D6. These individuals would require much longer amounts of time for their bodies to break down and eliminate Tramadol and tricyclic antidepressants and related drugs. It means that they will show an active medication within their bloodstream for more significant periods. Such individuals are at risk of taking different medications that will further decrease the effectiveness of breaking down the Tramadol. 

Additional considerations can impact the detection time of this drug. These include the following:

  • Dosages – a higher dose will require longer for your body to metabolize.
  • Metabolism – slower metabolisms can boost the time needed to break down Tramadol. This involves the diet, activities, and body compositions that all impact your metabolism.
  • Frequency of Utilization – Tramadol builds up within the body over additional dosages. Sometimes the prior dose will not have entirely broken down, which will cause the organism to need a longer time to metabolize subsequent dosages effectively.
  • Impaired Liver or Kidney Functions – If these bodily organs that the organism uses to eliminate waste are impaired, it will boost the quantity of time that Tramadol remains in your body for
  • Your Age – older adults always metabolize medicines at a slower rate, and they often take conflicting medications that will impact metabolism. They are also likely to suffer from impaired liver or kidney functions.

How You Can Get Tramadol Out From Your System

The sole means of evacuating Tramadol from your organism is to quit consuming the medication so that your body can process and then eliminate its presence naturally. For those who are worried that you have potentially overdosed on Tramadol, you can take Narcan that you can purchase at your area health department in the form of a nasal spray. This will reduce the hazardous impacts on your respiratory system of taking too much Tramadol. Beware that it will not expedite the Tramadol elimination, though. You might require additional Naloxone (Narcan) if sufficient quantities of overdosed Tramadol stay in the body.